One of the founding members of the iconic band The B-52s is back with a very queer new single.

Kate Pierson is slated to release a solo album, called “Guitars and Microphones” and executive produced by hit maker Sia, on February 17, 2015. In anticipation of this release, Pierson dropped her first single and video for “Mister Sister” — a track that she is dubbing a “trans[gender] anthem.”

“‘Mister Sister’ is inspired by all who are transgender and LGB, multi-dimensional and still transcending,” she told The Huffington Post in an email. “I hope it becomes a trans anthem, but it’s really meant to empower anyone who feels ‘betrayed by the mirror.'”

We’re loving this new single from Pierson and as an added bonus, the video features Fred Armisen of “Saturday Night Live” and “Portlandia” fame.

Check out the video for “Mister Sister” above. For more from Pierson, including info about the new album, follow her on Twitter.